Name	Flags	Card.	Type	Description & Constraints
MedicationStatement		0..*	MedicationStatement	Elenco dei Farmaci o Integratori assunti dal paziente dom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated dom-5: If a resource is contained in another resource, it SHALL NOT have a security label dom-6: A resource should have narrative for robust management
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created ele-1: All FHIR elements must have a @value or children
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
status	?!SΣ	1..1	code	Stato dell'assunzione del Farmaco (es. attivo, completato, interrotto) Binding: Medication Status Codes (required): A coded concept indicating the current status of a MedicationStatement. ele-1: All FHIR elements must have a @value or children
statusReason		0..*	CodeableConcept	Motivo dell'interruzione o modifica della terapia Binding: SNOMEDCTDrugTherapyStatusCodes (example): A coded concept indicating the reason for the status of the statement. ele-1: All FHIR elements must have a @value or children
medication[x]	Σ	1..1	Reference(Medication_Rigoletto)	Farmaco o Integratore assunto ele-1: All FHIR elements must have a @value or children
subject	Σ	1..1	Reference(Pazient_Rigoletto)	Paziente che assume il farmaco ele-1: All FHIR elements must have a @value or children
Slices for effective[x]	SΣ	1..1		Intervallo temporale in cui il Farmaco è stato assunto Slice: Unordered, Open by type:$this ele-1: All FHIR elements must have a @value or children
effectiveDateTime			dateTime
effectivePeriod			Period
effective[x]:effectivePeriod	Σ	0..1	Period	Periodo di assunzione del farmaco ele-1: All FHIR elements must have a @value or children
start	SΣC	1..1	dateTime	Data di inizio dell'assunzione del Farmaco ele-1: All FHIR elements must have a @value or children
dosage	S	0..*	Dosage	Dettagli sul dosaggio del Farmaco assunto ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
timing	SΣ	1..1	Timing	When medication should be administered ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
route	SΣ	1..1	CodeableConcept	How drug should enter body Binding: Dosage direction VS (required) ele-1: All FHIR elements must have a @value or children
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationStatement.status	required	Medication Status Codes http://hl7.org/fhir/ValueSet/medication-statement-status|4.0.1 from the FHIR Standard
MedicationStatement.statusReason	example	SNOMEDCTDrugTherapyStatusCodes http://hl7.org/fhir/ValueSet/reason-medication-status-codes from the FHIR Standard
MedicationStatement.dosage.route	required	DOSDIR https://rigoletto.na.icar.cnr.it/ValueSet/DOSDIR from this IG

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationStatement	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationStatement	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationStatement	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

Name	Flags	Card.	Type	Description & Constraints
MedicationStatement		0..*	MedicationStatement	Elenco dei Farmaci o Integratori assunti dal paziente
status	S	1..1	code	Stato dell'assunzione del Farmaco (es. attivo, completato, interrotto)
statusReason		0..*	CodeableConcept	Motivo dell'interruzione o modifica della terapia
medication[x]		1..1	Reference(Medication_Rigoletto)	Farmaco o Integratore assunto
subject		1..1	Reference(Pazient_Rigoletto)	Paziente che assume il farmaco
Slices for effective[x]	S	1..1	dateTime, Period	Intervallo temporale in cui il Farmaco è stato assunto Slice: Unordered, Open by type:$this
effective[x]:effectivePeriod		0..1	Period	Periodo di assunzione del farmaco
start	S	1..1	dateTime	Data di inizio dell'assunzione del Farmaco
dosage	S	0..*	Dosage	Dettagli sul dosaggio del Farmaco assunto
timing	S	1..1	Timing	When medication should be administered
repeat
when		0..*	code	Code for time period of occurrence Binding: EventTiming (required)
route	S	1..1	CodeableConcept	How drug should enter body Binding: Dosage direction VS (required)
Documentation for this format

Terminology Bindings (Differential)

Path	Conformance	ValueSet	URI
MedicationStatement.dosage.timing.repeat.when	required	EventTiming http://hl7.org/fhir/ValueSet/event-timing from the FHIR Standard
MedicationStatement.dosage.route	required	DOSDIR https://rigoletto.na.icar.cnr.it/ValueSet/DOSDIR from this IG

Name	Flags	Card.	Type	Description & Constraints
MedicationStatement		0..*	MedicationStatement	Elenco dei Farmaci o Integratori assunti dal paziente
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	0..*	Identifier	External identifier
basedOn	Σ	0..*	Reference(MedicationRequest | CarePlan | ServiceRequest)	Fulfils plan, proposal or order
partOf	Σ	0..*	Reference(MedicationAdministration | MedicationDispense | MedicationStatement | Procedure | Observation)	Part of referenced event
status	?!SΣ	1..1	code	Stato dell'assunzione del Farmaco (es. attivo, completato, interrotto) Binding: Medication Status Codes (required): A coded concept indicating the current status of a MedicationStatement.
statusReason		0..*	CodeableConcept	Motivo dell'interruzione o modifica della terapia Binding: SNOMEDCTDrugTherapyStatusCodes (example): A coded concept indicating the reason for the status of the statement.
category	Σ	0..1	CodeableConcept	Type of medication usage Binding: Medication usage category codes (preferred): A coded concept identifying where the medication included in the MedicationStatement is expected to be consumed or administered.
medication[x]	Σ	1..1	Reference(Medication_Rigoletto)	Farmaco o Integratore assunto
subject	Σ	1..1	Reference(Pazient_Rigoletto)	Paziente che assume il farmaco
context	Σ	0..1	Reference(Encounter | EpisodeOfCare)	Encounter / Episode associated with MedicationStatement
Slices for effective[x]	SΣ	1..1		Intervallo temporale in cui il Farmaco è stato assunto Slice: Unordered, Open by type:$this
effectiveDateTime			dateTime
effectivePeriod			Period
effective[x]:effectivePeriod	Σ	0..1	Period	Periodo di assunzione del farmaco
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
start	SΣC	1..1	dateTime	Data di inizio dell'assunzione del Farmaco
end	ΣC	0..1	dateTime	End time with inclusive boundary, if not ongoing
dateAsserted	Σ	0..1	dateTime	When the statement was asserted?
informationSource		0..1	Reference(Patient | Practitioner | PractitionerRole | RelatedPerson | Organization)	Person or organization that provided the information about the taking of this medication
derivedFrom		0..*	Reference(Resource)	Additional supporting information
reasonCode		0..*	CodeableConcept	Reason for why the medication is being/was taken Binding: Condition/Problem/DiagnosisCodes (example): A coded concept identifying why the medication is being taken.
reasonReference		0..*	Reference(Condition | Observation | DiagnosticReport)	Condition or observation that supports why the medication is being/was taken
note		0..*	Annotation	Further information about the statement
dosage	S	0..*	Dosage	Dettagli sul dosaggio del Farmaco assunto
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequence	Σ	0..1	integer	The order of the dosage instructions
text	Σ	0..1	string	Free text dosage instructions e.g. SIG
additionalInstruction	Σ	0..*	CodeableConcept	Supplemental instruction or warnings to the patient - e.g. "with meals", "may cause drowsiness" Binding: SNOMEDCTAdditionalDosageInstructions (example): A coded concept identifying additional instructions such as "take with water" or "avoid operating heavy machinery".
patientInstruction	Σ	0..1	string	Patient or consumer oriented instructions
timing	SΣ	1..1	Timing	When medication should be administered
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
event	Σ	0..*	dateTime	When the event occurs
repeat	ΣC	0..1	Element	When the event is to occur tim-1: if there's a duration, there needs to be duration units tim-2: if there's a period, there needs to be period units tim-4: duration SHALL be a non-negative value tim-5: period SHALL be a non-negative value tim-6: If there's a periodMax, there must be a period tim-7: If there's a durationMax, there must be a duration tim-8: If there's a countMax, there must be a count tim-9: If there's an offset, there must be a when (and not C, CM, CD, CV) tim-10: If there's a timeOfDay, there cannot be a when, or vice versa
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
bounds[x]	Σ	0..1		Length/Range of lengths, or (Start and/or end) limits
boundsDuration			Duration
boundsRange			Range
boundsPeriod			Period
count	Σ	0..1	positiveInt	Number of times to repeat
countMax	Σ	0..1	positiveInt	Maximum number of times to repeat
duration	Σ	0..1	decimal	How long when it happens
durationMax	Σ	0..1	decimal	How long when it happens (Max)
durationUnit	Σ	0..1	code	s | min | h | d | wk | mo | a - unit of time (UCUM) Binding: UnitsOfTime (required): A unit of time (units from UCUM).
frequency	Σ	0..1	positiveInt	Event occurs frequency times per period
frequencyMax	Σ	0..1	positiveInt	Event occurs up to frequencyMax times per period
period	Σ	0..1	decimal	Event occurs frequency times per period
periodMax	Σ	0..1	decimal	Upper limit of period (3-4 hours)
periodUnit	Σ	0..1	code	s | min | h | d | wk | mo | a - unit of time (UCUM) Binding: UnitsOfTime (required): A unit of time (units from UCUM).
dayOfWeek	Σ	0..*	code	mon | tue | wed | thu | fri | sat | sun Binding: DaysOfWeek (required)
timeOfDay	Σ	0..*	time	Time of day for action
when	Σ	0..*	code	Code for time period of occurrence Binding: EventTiming (required)
offset	Σ	0..1	unsignedInt	Minutes from event (before or after)
code	Σ	0..1	CodeableConcept	BID | TID | QID | AM | PM | QD | QOD | + Binding: TimingAbbreviation (preferred): Code for a known / defined timing pattern.
asNeeded[x]	Σ	0..1		Take "as needed" (for x) Binding: SNOMEDCTMedicationAsNeededReasonCodes (example): A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc.
asNeededBoolean			boolean
asNeededCodeableConcept			CodeableConcept
site	Σ	0..1	CodeableConcept	Body site to administer to Binding: SNOMEDCTAnatomicalStructureForAdministrationSiteCodes (example): A coded concept describing the site location the medicine enters into or onto the body.
route	SΣ	1..1	CodeableConcept	How drug should enter body Binding: Dosage direction VS (required)
method	Σ	0..1	CodeableConcept	Technique for administering medication Binding: SNOMEDCTAdministrationMethodCodes (example): A coded concept describing the technique by which the medicine is administered.
doseAndRate	Σ	0..*	Element	Amount of medication administered
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
type	Σ	0..1	CodeableConcept	The kind of dose or rate specified Binding: DoseAndRateType (example): The kind of dose or rate specified.
dose[x]	Σ	0..1		Amount of medication per dose
doseRange			Range
doseQuantity			Quantity(SimpleQuantity)
rate[x]	Σ	0..1		Amount of medication per unit of time
rateRatio			Ratio
rateRange			Range
rateQuantity			Quantity(SimpleQuantity)
maxDosePerPeriod	Σ	0..1	Ratio	Upper limit on medication per unit of time
maxDosePerAdministration	Σ	0..1	SimpleQuantity	Upper limit on medication per administration
maxDosePerLifetime	Σ	0..1	SimpleQuantity	Upper limit on medication per lifetime of the patient
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationStatement.language	preferred	CommonLanguages http://hl7.org/fhir/ValueSet/languages from the FHIR Standard Additional Bindings Purpose AllLanguages Max Binding
MedicationStatement.status	required	Medication Status Codes http://hl7.org/fhir/ValueSet/medication-statement-status|4.0.1 from the FHIR Standard
MedicationStatement.statusReason	example	SNOMEDCTDrugTherapyStatusCodes http://hl7.org/fhir/ValueSet/reason-medication-status-codes from the FHIR Standard
MedicationStatement.category	preferred	Medication usage category codes http://hl7.org/fhir/ValueSet/medication-statement-category from the FHIR Standard
MedicationStatement.reasonCode	example	Condition/Problem/DiagnosisCodes http://hl7.org/fhir/ValueSet/condition-code from the FHIR Standard
MedicationStatement.dosage.additionalInstruction	example	SNOMEDCTAdditionalDosageInstructions http://hl7.org/fhir/ValueSet/additional-instruction-codes from the FHIR Standard
MedicationStatement.dosage.timing.repeat.durationUnit	required	UnitsOfTime http://hl7.org/fhir/ValueSet/units-of-time|4.0.1 from the FHIR Standard
MedicationStatement.dosage.timing.repeat.periodUnit	required	UnitsOfTime http://hl7.org/fhir/ValueSet/units-of-time|4.0.1 from the FHIR Standard
MedicationStatement.dosage.timing.repeat.dayOfWeek	required	DaysOfWeek http://hl7.org/fhir/ValueSet/days-of-week|4.0.1 from the FHIR Standard
MedicationStatement.dosage.timing.repeat.when	required	EventTiming http://hl7.org/fhir/ValueSet/event-timing from the FHIR Standard
MedicationStatement.dosage.timing.code	preferred	TimingAbbreviation http://hl7.org/fhir/ValueSet/timing-abbreviation from the FHIR Standard
MedicationStatement.dosage.asNeeded[x]	example	SNOMEDCTMedicationAsNeededReasonCodes http://hl7.org/fhir/ValueSet/medication-as-needed-reason from the FHIR Standard
MedicationStatement.dosage.site	example	SNOMEDCTAnatomicalStructureForAdministrationSiteCodes http://hl7.org/fhir/ValueSet/approach-site-codes from the FHIR Standard
MedicationStatement.dosage.route	required	DOSDIR https://rigoletto.na.icar.cnr.it/ValueSet/DOSDIR from this IG
MedicationStatement.dosage.method	example	SNOMEDCTAdministrationMethodCodes http://hl7.org/fhir/ValueSet/administration-method-codes from the FHIR Standard
MedicationStatement.dosage.doseAndRate.type	example	DoseAndRateType http://hl7.org/fhir/ValueSet/dose-rate-type from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationStatement	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationStatement	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationStatement	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()
tim-1	error	MedicationStatement.dosage.timing.repeat	if there's a duration, there needs to be duration units : duration.empty() or durationUnit.exists()
tim-2	error	MedicationStatement.dosage.timing.repeat	if there's a period, there needs to be period units : period.empty() or periodUnit.exists()
tim-4	error	MedicationStatement.dosage.timing.repeat	duration SHALL be a non-negative value : duration.exists() implies duration >= 0
tim-5	error	MedicationStatement.dosage.timing.repeat	period SHALL be a non-negative value : period.exists() implies period >= 0
tim-6	error	MedicationStatement.dosage.timing.repeat	If there's a periodMax, there must be a period : periodMax.empty() or period.exists()
tim-7	error	MedicationStatement.dosage.timing.repeat	If there's a durationMax, there must be a duration : durationMax.empty() or duration.exists()
tim-8	error	MedicationStatement.dosage.timing.repeat	If there's a countMax, there must be a count : countMax.empty() or count.exists()
tim-9	error	MedicationStatement.dosage.timing.repeat	If there's an offset, there must be a when (and not C, CM, CD, CV) : offset.empty() or (when.exists() and ((when in ('C' | 'CM' | 'CD' | 'CV')).not()))
tim-10	error	MedicationStatement.dosage.timing.repeat	If there's a timeOfDay, there cannot be a when, or vice versa : timeOfDay.empty() or when.empty()

Summary

Mandatory: 1 element(3 nested mandatory elements)
Must-Support: 6 elements

Structures

This structure refers to these other structures:

• Medication_Rigoletto (https://rigoletto.na.icar.cnr.it/StructureDefinition/medication-rigoletto)
• Pazient_Rigoletto (https://rigoletto.na.icar.cnr.it/StructureDefinition/patient-rigoletto)

Slices

This structure defines the following Slices:

• The element 1 is sliced based on the value of MedicationStatement.effective[x]

Name	Flags	Card.	Type	Description & Constraints
MedicationStatement		0..*	MedicationStatement	Elenco dei Farmaci o Integratori assunti dal paziente dom-2: If the resource is contained in another resource, it SHALL NOT contain nested Resources dom-3: If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource dom-4: If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated dom-5: If a resource is contained in another resource, it SHALL NOT have a security label dom-6: A resource should have narrative for robust management
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created ele-1: All FHIR elements must have a @value or children
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
status	?!SΣ	1..1	code	Stato dell'assunzione del Farmaco (es. attivo, completato, interrotto) Binding: Medication Status Codes (required): A coded concept indicating the current status of a MedicationStatement. ele-1: All FHIR elements must have a @value or children
statusReason		0..*	CodeableConcept	Motivo dell'interruzione o modifica della terapia Binding: SNOMEDCTDrugTherapyStatusCodes (example): A coded concept indicating the reason for the status of the statement. ele-1: All FHIR elements must have a @value or children
medication[x]	Σ	1..1	Reference(Medication_Rigoletto)	Farmaco o Integratore assunto ele-1: All FHIR elements must have a @value or children
subject	Σ	1..1	Reference(Pazient_Rigoletto)	Paziente che assume il farmaco ele-1: All FHIR elements must have a @value or children
Slices for effective[x]	SΣ	1..1		Intervallo temporale in cui il Farmaco è stato assunto Slice: Unordered, Open by type:$this ele-1: All FHIR elements must have a @value or children
effectiveDateTime			dateTime
effectivePeriod			Period
effective[x]:effectivePeriod	Σ	0..1	Period	Periodo di assunzione del farmaco ele-1: All FHIR elements must have a @value or children
start	SΣC	1..1	dateTime	Data di inizio dell'assunzione del Farmaco ele-1: All FHIR elements must have a @value or children
dosage	S	0..*	Dosage	Dettagli sul dosaggio del Farmaco assunto ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
timing	SΣ	1..1	Timing	When medication should be administered ele-1: All FHIR elements must have a @value or children
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized ele-1: All FHIR elements must have a @value or children ext-1: Must have either extensions or value[x], not both
route	SΣ	1..1	CodeableConcept	How drug should enter body Binding: Dosage direction VS (required) ele-1: All FHIR elements must have a @value or children
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationStatement.status	required	Medication Status Codes http://hl7.org/fhir/ValueSet/medication-statement-status|4.0.1 from the FHIR Standard
MedicationStatement.statusReason	example	SNOMEDCTDrugTherapyStatusCodes http://hl7.org/fhir/ValueSet/reason-medication-status-codes from the FHIR Standard
MedicationStatement.dosage.route	required	DOSDIR https://rigoletto.na.icar.cnr.it/ValueSet/DOSDIR from this IG

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationStatement	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationStatement	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationStatement	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()

Name	Flags	Card.	Type	Description & Constraints
MedicationStatement		0..*	MedicationStatement	Elenco dei Farmaci o Integratori assunti dal paziente
status	S	1..1	code	Stato dell'assunzione del Farmaco (es. attivo, completato, interrotto)
statusReason		0..*	CodeableConcept	Motivo dell'interruzione o modifica della terapia
medication[x]		1..1	Reference(Medication_Rigoletto)	Farmaco o Integratore assunto
subject		1..1	Reference(Pazient_Rigoletto)	Paziente che assume il farmaco
Slices for effective[x]	S	1..1	dateTime, Period	Intervallo temporale in cui il Farmaco è stato assunto Slice: Unordered, Open by type:$this
effective[x]:effectivePeriod		0..1	Period	Periodo di assunzione del farmaco
start	S	1..1	dateTime	Data di inizio dell'assunzione del Farmaco
dosage	S	0..*	Dosage	Dettagli sul dosaggio del Farmaco assunto
timing	S	1..1	Timing	When medication should be administered
repeat
when		0..*	code	Code for time period of occurrence Binding: EventTiming (required)
route	S	1..1	CodeableConcept	How drug should enter body Binding: Dosage direction VS (required)
Documentation for this format

Terminology Bindings (Differential)

Path	Conformance	ValueSet	URI
MedicationStatement.dosage.timing.repeat.when	required	EventTiming http://hl7.org/fhir/ValueSet/event-timing from the FHIR Standard
MedicationStatement.dosage.route	required	DOSDIR https://rigoletto.na.icar.cnr.it/ValueSet/DOSDIR from this IG

Name	Flags	Card.	Type	Description & Constraints
MedicationStatement		0..*	MedicationStatement	Elenco dei Farmaci o Integratori assunti dal paziente
id	Σ	0..1	id	Logical id of this artifact
meta	Σ	0..1	Meta	Metadata about the resource
implicitRules	?!Σ	0..1	uri	A set of rules under which this content was created
language		0..1	code	Language of the resource content Binding: CommonLanguages (preferred): A human language. Additional Bindings Purpose AllLanguages Max Binding
text		0..1	Narrative	Text summary of the resource, for human interpretation
contained		0..*	Resource	Contained, inline Resources
extension		0..*	Extension	Additional content defined by implementations
modifierExtension	?!	0..*	Extension	Extensions that cannot be ignored
identifier	Σ	0..*	Identifier	External identifier
basedOn	Σ	0..*	Reference(MedicationRequest | CarePlan | ServiceRequest)	Fulfils plan, proposal or order
partOf	Σ	0..*	Reference(MedicationAdministration | MedicationDispense | MedicationStatement | Procedure | Observation)	Part of referenced event
status	?!SΣ	1..1	code	Stato dell'assunzione del Farmaco (es. attivo, completato, interrotto) Binding: Medication Status Codes (required): A coded concept indicating the current status of a MedicationStatement.
statusReason		0..*	CodeableConcept	Motivo dell'interruzione o modifica della terapia Binding: SNOMEDCTDrugTherapyStatusCodes (example): A coded concept indicating the reason for the status of the statement.
category	Σ	0..1	CodeableConcept	Type of medication usage Binding: Medication usage category codes (preferred): A coded concept identifying where the medication included in the MedicationStatement is expected to be consumed or administered.
medication[x]	Σ	1..1	Reference(Medication_Rigoletto)	Farmaco o Integratore assunto
subject	Σ	1..1	Reference(Pazient_Rigoletto)	Paziente che assume il farmaco
context	Σ	0..1	Reference(Encounter | EpisodeOfCare)	Encounter / Episode associated with MedicationStatement
Slices for effective[x]	SΣ	1..1		Intervallo temporale in cui il Farmaco è stato assunto Slice: Unordered, Open by type:$this
effectiveDateTime			dateTime
effectivePeriod			Period
effective[x]:effectivePeriod	Σ	0..1	Period	Periodo di assunzione del farmaco
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
start	SΣC	1..1	dateTime	Data di inizio dell'assunzione del Farmaco
end	ΣC	0..1	dateTime	End time with inclusive boundary, if not ongoing
dateAsserted	Σ	0..1	dateTime	When the statement was asserted?
informationSource		0..1	Reference(Patient | Practitioner | PractitionerRole | RelatedPerson | Organization)	Person or organization that provided the information about the taking of this medication
derivedFrom		0..*	Reference(Resource)	Additional supporting information
reasonCode		0..*	CodeableConcept	Reason for why the medication is being/was taken Binding: Condition/Problem/DiagnosisCodes (example): A coded concept identifying why the medication is being taken.
reasonReference		0..*	Reference(Condition | Observation | DiagnosticReport)	Condition or observation that supports why the medication is being/was taken
note		0..*	Annotation	Further information about the statement
dosage	S	0..*	Dosage	Dettagli sul dosaggio del Farmaco assunto
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
sequence	Σ	0..1	integer	The order of the dosage instructions
text	Σ	0..1	string	Free text dosage instructions e.g. SIG
additionalInstruction	Σ	0..*	CodeableConcept	Supplemental instruction or warnings to the patient - e.g. "with meals", "may cause drowsiness" Binding: SNOMEDCTAdditionalDosageInstructions (example): A coded concept identifying additional instructions such as "take with water" or "avoid operating heavy machinery".
patientInstruction	Σ	0..1	string	Patient or consumer oriented instructions
timing	SΣ	1..1	Timing	When medication should be administered
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
modifierExtension	?!Σ	0..*	Extension	Extensions that cannot be ignored even if unrecognized
event	Σ	0..*	dateTime	When the event occurs
repeat	ΣC	0..1	Element	When the event is to occur tim-1: if there's a duration, there needs to be duration units tim-2: if there's a period, there needs to be period units tim-4: duration SHALL be a non-negative value tim-5: period SHALL be a non-negative value tim-6: If there's a periodMax, there must be a period tim-7: If there's a durationMax, there must be a duration tim-8: If there's a countMax, there must be a count tim-9: If there's an offset, there must be a when (and not C, CM, CD, CV) tim-10: If there's a timeOfDay, there cannot be a when, or vice versa
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
bounds[x]	Σ	0..1		Length/Range of lengths, or (Start and/or end) limits
boundsDuration			Duration
boundsRange			Range
boundsPeriod			Period
count	Σ	0..1	positiveInt	Number of times to repeat
countMax	Σ	0..1	positiveInt	Maximum number of times to repeat
duration	Σ	0..1	decimal	How long when it happens
durationMax	Σ	0..1	decimal	How long when it happens (Max)
durationUnit	Σ	0..1	code	s | min | h | d | wk | mo | a - unit of time (UCUM) Binding: UnitsOfTime (required): A unit of time (units from UCUM).
frequency	Σ	0..1	positiveInt	Event occurs frequency times per period
frequencyMax	Σ	0..1	positiveInt	Event occurs up to frequencyMax times per period
period	Σ	0..1	decimal	Event occurs frequency times per period
periodMax	Σ	0..1	decimal	Upper limit of period (3-4 hours)
periodUnit	Σ	0..1	code	s | min | h | d | wk | mo | a - unit of time (UCUM) Binding: UnitsOfTime (required): A unit of time (units from UCUM).
dayOfWeek	Σ	0..*	code	mon | tue | wed | thu | fri | sat | sun Binding: DaysOfWeek (required)
timeOfDay	Σ	0..*	time	Time of day for action
when	Σ	0..*	code	Code for time period of occurrence Binding: EventTiming (required)
offset	Σ	0..1	unsignedInt	Minutes from event (before or after)
code	Σ	0..1	CodeableConcept	BID | TID | QID | AM | PM | QD | QOD | + Binding: TimingAbbreviation (preferred): Code for a known / defined timing pattern.
asNeeded[x]	Σ	0..1		Take "as needed" (for x) Binding: SNOMEDCTMedicationAsNeededReasonCodes (example): A coded concept identifying the precondition that should be met or evaluated prior to consuming or administering a medication dose. For example "pain", "30 minutes prior to sexual intercourse", "on flare-up" etc.
asNeededBoolean			boolean
asNeededCodeableConcept			CodeableConcept
site	Σ	0..1	CodeableConcept	Body site to administer to Binding: SNOMEDCTAnatomicalStructureForAdministrationSiteCodes (example): A coded concept describing the site location the medicine enters into or onto the body.
route	SΣ	1..1	CodeableConcept	How drug should enter body Binding: Dosage direction VS (required)
method	Σ	0..1	CodeableConcept	Technique for administering medication Binding: SNOMEDCTAdministrationMethodCodes (example): A coded concept describing the technique by which the medicine is administered.
doseAndRate	Σ	0..*	Element	Amount of medication administered
id		0..1	string	Unique id for inter-element referencing
extension		0..*	Extension	Additional content defined by implementations Slice: Unordered, Open by value:url
type	Σ	0..1	CodeableConcept	The kind of dose or rate specified Binding: DoseAndRateType (example): The kind of dose or rate specified.
dose[x]	Σ	0..1		Amount of medication per dose
doseRange			Range
doseQuantity			Quantity(SimpleQuantity)
rate[x]	Σ	0..1		Amount of medication per unit of time
rateRatio			Ratio
rateRange			Range
rateQuantity			Quantity(SimpleQuantity)
maxDosePerPeriod	Σ	0..1	Ratio	Upper limit on medication per unit of time
maxDosePerAdministration	Σ	0..1	SimpleQuantity	Upper limit on medication per administration
maxDosePerLifetime	Σ	0..1	SimpleQuantity	Upper limit on medication per lifetime of the patient
Documentation for this format

Terminology Bindings

Path	Conformance	ValueSet	URI
MedicationStatement.language	preferred	CommonLanguages http://hl7.org/fhir/ValueSet/languages from the FHIR Standard Additional Bindings Purpose AllLanguages Max Binding
MedicationStatement.status	required	Medication Status Codes http://hl7.org/fhir/ValueSet/medication-statement-status|4.0.1 from the FHIR Standard
MedicationStatement.statusReason	example	SNOMEDCTDrugTherapyStatusCodes http://hl7.org/fhir/ValueSet/reason-medication-status-codes from the FHIR Standard
MedicationStatement.category	preferred	Medication usage category codes http://hl7.org/fhir/ValueSet/medication-statement-category from the FHIR Standard
MedicationStatement.reasonCode	example	Condition/Problem/DiagnosisCodes http://hl7.org/fhir/ValueSet/condition-code from the FHIR Standard
MedicationStatement.dosage.additionalInstruction	example	SNOMEDCTAdditionalDosageInstructions http://hl7.org/fhir/ValueSet/additional-instruction-codes from the FHIR Standard
MedicationStatement.dosage.timing.repeat.durationUnit	required	UnitsOfTime http://hl7.org/fhir/ValueSet/units-of-time|4.0.1 from the FHIR Standard
MedicationStatement.dosage.timing.repeat.periodUnit	required	UnitsOfTime http://hl7.org/fhir/ValueSet/units-of-time|4.0.1 from the FHIR Standard
MedicationStatement.dosage.timing.repeat.dayOfWeek	required	DaysOfWeek http://hl7.org/fhir/ValueSet/days-of-week|4.0.1 from the FHIR Standard
MedicationStatement.dosage.timing.repeat.when	required	EventTiming http://hl7.org/fhir/ValueSet/event-timing from the FHIR Standard
MedicationStatement.dosage.timing.code	preferred	TimingAbbreviation http://hl7.org/fhir/ValueSet/timing-abbreviation from the FHIR Standard
MedicationStatement.dosage.asNeeded[x]	example	SNOMEDCTMedicationAsNeededReasonCodes http://hl7.org/fhir/ValueSet/medication-as-needed-reason from the FHIR Standard
MedicationStatement.dosage.site	example	SNOMEDCTAnatomicalStructureForAdministrationSiteCodes http://hl7.org/fhir/ValueSet/approach-site-codes from the FHIR Standard
MedicationStatement.dosage.route	required	DOSDIR https://rigoletto.na.icar.cnr.it/ValueSet/DOSDIR from this IG
MedicationStatement.dosage.method	example	SNOMEDCTAdministrationMethodCodes http://hl7.org/fhir/ValueSet/administration-method-codes from the FHIR Standard
MedicationStatement.dosage.doseAndRate.type	example	DoseAndRateType http://hl7.org/fhir/ValueSet/dose-rate-type from the FHIR Standard

Constraints

Id	Grade	Path(s)	Details	Requirements
dom-2	error	MedicationStatement	If the resource is contained in another resource, it SHALL NOT contain nested Resources : contained.contained.empty()
dom-3	error	MedicationStatement	If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource or SHALL refer to the containing resource : contained.where((('#'+id in (%resource.descendants().reference | %resource.descendants().as(canonical) | %resource.descendants().as(uri) | %resource.descendants().as(url))) or descendants().where(reference = '#').exists() or descendants().where(as(canonical) = '#').exists() or descendants().where(as(canonical) = '#').exists()).not()).trace('unmatched', id).empty()
dom-4	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated : contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()
dom-5	error	MedicationStatement	If a resource is contained in another resource, it SHALL NOT have a security label : contained.meta.security.empty()
dom-6	best practice	MedicationStatement	A resource should have narrative for robust management : text.`div`.exists()
ele-1	error	**ALL** elements	All FHIR elements must have a @value or children : hasValue() or (children().count() > id.count())
ext-1	error	**ALL** extensions	Must have either extensions or value[x], not both : extension.exists() != value.exists()
tim-1	error	MedicationStatement.dosage.timing.repeat	if there's a duration, there needs to be duration units : duration.empty() or durationUnit.exists()
tim-2	error	MedicationStatement.dosage.timing.repeat	if there's a period, there needs to be period units : period.empty() or periodUnit.exists()
tim-4	error	MedicationStatement.dosage.timing.repeat	duration SHALL be a non-negative value : duration.exists() implies duration >= 0
tim-5	error	MedicationStatement.dosage.timing.repeat	period SHALL be a non-negative value : period.exists() implies period >= 0
tim-6	error	MedicationStatement.dosage.timing.repeat	If there's a periodMax, there must be a period : periodMax.empty() or period.exists()
tim-7	error	MedicationStatement.dosage.timing.repeat	If there's a durationMax, there must be a duration : durationMax.empty() or duration.exists()
tim-8	error	MedicationStatement.dosage.timing.repeat	If there's a countMax, there must be a count : countMax.empty() or count.exists()
tim-9	error	MedicationStatement.dosage.timing.repeat	If there's an offset, there must be a when (and not C, CM, CD, CV) : offset.empty() or (when.exists() and ((when in ('C' | 'CM' | 'CD' | 'CV')).not()))
tim-10	error	MedicationStatement.dosage.timing.repeat	If there's a timeOfDay, there cannot be a when, or vice versa : timeOfDay.empty() or when.empty()

Summary

Mandatory: 1 element(3 nested mandatory elements)
Must-Support: 6 elements

Structures

This structure refers to these other structures:

• Medication_Rigoletto (https://rigoletto.na.icar.cnr.it/StructureDefinition/medication-rigoletto)
• Pazient_Rigoletto (https://rigoletto.na.icar.cnr.it/StructureDefinition/patient-rigoletto)

Slices

This structure defines the following Slices:

• The element 1 is sliced based on the value of MedicationStatement.effective[x]